Alfredo A. Santillan, M.D., MPH PDFPrint-friendly PDF

Alfredo Santillan

Provider Type: Physician


  • Surgical Oncology

Clinic Location:

General Summary:

Background / Education:

  • Fellowship in Surgical Oncology
    Moffitt Cancer Center, University of South Florida, Tampa, FL
  • Fellowship in Head and Neck Oncology
    Allando Ballantyne Fellowship in Head and Neck Surgery at M.D. Anderson Cancer Center, University of Texas, Houston, TX
  • Residency in General Surgery
    Texas Tech University Health Sciences Center, El Paso, TX
  • Master of Public Health, Quantitative Methods
    Harvard T.H. Chan School of Public Health, Boston, MA
  • Medical Doctorate
    Monterrey Institute of Technology and Higher Education, Monterrey, N.L., México

Medical Practice:

Community Service:

Memberships / Honors / Awards:

  • American Association of Endocrine Surgeons
  • American College of Surgeons
  • American Head and Neck Society
  • American Society of Breast Surgeons
  • American Society of Clinical Oncology
  • Society of Surgical Oncology

Research Interest:

Dr. Santillan’s areas of expertise include oncologic and endocrine surgery with emphasis on surgical diseases of the breast, thyroid, parathyroid, adrenal, colon, melanoma, pancreas and sarcoma. He has practiced in San Antonio since 2009 and is recognized as a leader in cancer and endocrine surgery with extensive surgical experience.

He is a Hidden Scar trained surgeon on advanced minimally invasive and minimal access surgical approaches that deliver optimal clinical and aesthetic outcomes for patients with breast cancer.

Surgery Locations:

  • Methodist Hospital
  • St. Lukes Baptist Hospital
  • CHRISTUS Santa Rosa Hospital - Medical Center
  • CHRISTUS Santa Rosa Hospital - Westover Hills
  • Methodist Stone Oak Hospital
  • Methodist Specialty and Transplant Hospital
  • Metropolitan Methodist Hospital

Conditions & Procedures

Endocrine: Thyroid, Parathyroid, Adrenal

  • Thyroidectomy, Central neck lymph node dissection, Lateral neck lymph node dissection, Recurrent laryngeal nerve monitoring, Minimal invasive parathyroidectomy, Robotic and laparoscopic adrenalectomy
  • High volume category of thyroid procedures


  • Lumpectomy, Partial mastectomy, Mastectomy, Skin and nipple sparing mastectomy, Sentinel lymph node biopsy, Axillary lymph node dissection
  • Hidden Scar mastectomy, Hidden Scar lumpectomy
  • Placement of SAVI for five-day high dose rate (HDR) brachytherapy treatment after lumpectomy, implanted port placement
  • Genetic Testing for hereditary breast cancer (BRCA Gene)

Coordination with reconstructive/plastic surgery

Dr. Santillan works closely with PRMA Center for Advanced Breast Reconstruction which combines reconstructive excellence with cosmetic surgery expertise. They strive to provide Dr. Santillan’s breast cancer patients the best and most natural results possible.

Melanoma & Soft Tissue Sarcoma

  • Excision of skin melanoma, skin graft after excision, Sentinel lymph node biopsy, Lymphadenectomy, Isolated limb infusion, Resection of sarcoma.

Complex Gastrointestinal Surgical Oncology & Pancreas

  • Gastric cancer
    • Total-Subtotal-Partial Gastrectomy
  • Small bowel & Colon Cancer
    • Laparoscopic right hemicolectomy, Laparoscopic subtotal colectomy, Robotic sigmoidectomy
  • Rectal Cancer
    • Robotic Low Anterior Resection, Robotic Abdominoperineal Resection, Robotic coloanal anastomosis
  • Pancreas
    • Distal pancreatectomy, Whipple procedure, Pancreatic enucleation
  • Liver
    • Hepatectomy
  • Peritoneal Cancer & Appendiceal Cancer
    • Cytoreductive surgery
    • HIPEC intraperitoneal chemotherapy

Other Personal Information:

He is a co-author of numerous publications and research projects with special interest in cancer biology is one of the few high thyroid volume surgeons in South Texas, according to the American Thyroid Association guidelines, with more than 100 thyroid surgeries per year.

Associated Physicians:

Dr. Brian works closely with two associated oncologists to treat breast cancer:

Lea K. Krekow, M.D.
Texas Oncology-Bedford

Lea Kathleen Krekow, M.D. specializes in medical oncology. She is board certified in medical oncology. Dr. Krekow has received numerous awards and honors including the American Society of Clinical Oncology Merit Award and during her residency...
Read more at the Texas Oncology website > 

Janice Tomberlin, M.D.
Texas Oncology-Bedford Edwards Cancer Center

Janice Tomberlin, M.D. specializes in breast cancer. She is board certified in radiation oncology by the American Board of Radiology...
Read more at the Texas Oncology website > 


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